Mouse IL-5 Antibody Pair Set (E-KAB-0567)
For research use only.
| Background |
Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival , differentiation , and chemotaxis of eosinophils.Acts also on activated and resting B-cells to induce immunoglobulin production , growth , and differentiation.Mechanistically , exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN , SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.
|
| Synonyms |
IL5, EDF, TRF, E-CSF, ESGF
|
| Swissprot | |
| Reactivity |
Mouse
|
| Specificity |
Detects Mouse IL-5 in ELISAs
|
| Applications |
ELISA
|
| Storage |
-20℃
|
| Expiration date |
12 months
|
Other Clones
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