Mouse CEACAM1 Antibody Pair Set (E-KAB-0728)
For research use only.
| Background |
CD66a,known as carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM-1),is a glycoprotein of the immunoglobulin superfamily and the carcinoembryonic antigen family. CEACAM-1 functions as an intercellular adhesion molecule,an angiogenic factor,and a tumor cell growth inhibitor. CEACAM-1 is expressed in multiple epithelial malignancies,including gastric cancer,colorectal cancer,and pancreatic cancer,as well as in NSC lung cancer and melanoma. CEACAM-1 comprises one N-terminal variable domain,six C2-like Ig domains and glycosylphosphatidylinositol (GPI) linker,which facilitate adhesion through homophilic and/or heterophilic (CEACAM1–CEACAM5) interactions. CEACAM-1 has a significant clinical role as a tumor marker for several tumors including gastrointestinal and respiratory malignancies. CEACAM-1 has variable roles in tumor initiation,progression,and metastasis.
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| Synonyms |
CEACAM-1, CEACAM1, CD66a, CEA, Meconium antigen 100
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| Swissprot | |
| Reactivity |
Mouse
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| Specificity |
Detects Mouse CEACAM1 in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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| Introduction |
This ELISA kit applies to the in vitro quantitative determination of Mouse CEACAM1 concentrations in serum, plasma and other biological fluids.
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