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For research use only.
| Background | Dipeptidyl carboxypeptidase that removes dipeptides from the C-terminus of a variety of circulating hormones , such as angiotensin I , bradykinin or enkephalins , thereby playing a key role in the regulation of blood pressure , electrolyte homeostasis or synaptic plasticity.Composed of two similar catalytic domains , each possessing a functional active site , with different selectivity for substrates.Plays a major role in the angiotensin-renin system that regulates blood pressure and sodium retention by the kidney by converting angiotensin I to angiotensin II , resulting in an increase of the vasoconstrictor activity of angiotensin.Also able to inactivate bradykinin , a potent vasodilator , and therefore enhance the blood pressure response.Acts as a regulator of synaptic transmission by mediating cleavage of neuropeptide hormones , such as substance P , neurotensin or enkephalins.Catalyzes degradation of different enkephalin neuropeptides ( Met-enkephalin , Leu-enkephalin , Met-enkephalin-Arg-Phe and possibly Met-enkephalin-Arg-Gly-Leu ) .Acts as a regulator of synaptic plasticity in the nucleus accumbens of the brain by mediating cleavage of Met-enkephalin-Arg-Phe , a strong ligand of Mu-type opioid receptor OPRM1 , into Met-enkephalin. |
| Synonyms | ACE1, CD143, DCP, DCP1, ICH, MVCD3 |
| Swissprot | |
| Reactivity | Mouse |
| Specificity | Detects Mouse ACE in ELISAs |
| Applications | ELISA |
| Storage | -20℃ |
| Expiration date | 12 months |
| Introduction | This Antibody Pair Kit applies to the sandwich ELISA assay. |
Other Clones
1 Results
Other Formats
1 Results
Biotin
