Monkey αFP Antibody Pair Set (E-KAB-0653)
For research use only.
| Background |
alpha-Fetoprotein ( AFP ) ;is albuminoid superfamily protein that is synthesized in the fetus primarily by the liver;yolk sac;and tissues of gastrointestinal origin. It is one of the earliest markers of the hepatocyte lineage. AFP acts as a carrier protein for steroids;bilirubin;fatty acids;retinoids;and flavonoids. In addition;it can exert immunosuppressive activity;regulate cell proliferation and apoptosis;initiate intracellular signaling;and contribute to cell invasion. Altered levels of both fetal and maternal AFP have been associated with hypothyroidism;autoimmune disorders;and heart defects. Low maternal serum AFP levels are associated with a higher incidence of Down syndrome;whereas higher levels are associated with spina bifida and anencephaly. Elevated AFP levels are also coincident with liver;stomach;and germ cell cancers.
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| Synonyms |
AFP, FETA, HPAFP, Alpha-fetoglobulin, oralpha fetal protein
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| Swissprot | |
| Reactivity |
Monkey
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| Specificity |
Detects Monkey αFP in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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