Monkey CTSB Antibody Pair Set (E-KAB-0665)
For research use only.
| Background |
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains , both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein ( APP ) . Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease , the most common cause of dementia. Overexpression of the encoded protein , which is a member of the peptidase C1 family , has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.
|
| Synonyms |
APPS, CPSB
|
| Swissprot | |
| Reactivity |
Monkey
|
| Specificity |
Detects Monkey CTSB in ELISAs
|
| Applications |
ELISA
|
| Storage |
-20℃
|
| Expiration date |
12 months
|
Other Clones
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