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For research use only.

Verified Samples Verified Samples in IHC: Human tonsil, Human colorectal cancer
Dilution IHC 1:50-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human MOB1A
Abbre MOB1A
Synonyms B1,  C2orf6,  Chromosome 2 open reading frame 6,  FLJ10788,  FLJ11595,  MATS1,  MO,  MOB kinase activator 1A,  MOB1,  MOB1 Mps One Binder homolog A,  MOB1 Mps One Binder kinase activator like 1B,  Mob1 alpha,  Mob1 homolog 1B,  Mob1A,  Mps One Binder kinase activator like 1B (yeast)
Swissprot
Cellular Localization Cytosol, Extracellular region or secreted, extracellular exosome, Nucleus, nucleolus.
Concentration 0.84 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cancer,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background MOB1 was first identified in yeast as a protein that binds to Mps with essential roles in the completion of mitosis and the maintenance of ploidy.Its Drosophila and mammalian homologs, Mats and MOB1, respectively, are involved in the Hippo signaling tumor suppressor pathway, which plays a critical role in organ size regulation and which has been implicated in cancer development .There are two MOB1 proteins in humans, MOB1α and MOB1β, that are encoded by two different genes but which have greater than 95% amino acid sequence identity.
Other Clones

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Unconjugated

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