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For research use only.

Verified Samples Verified Samples in IHC: Mouse brain, Rat brain
Dilution IHC 1:300-1:1000
Isotype IgG
Host Rabbit
Reactivity Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein corresponding to Mouse Myelin Basic Protein
Abbre MBP
Synonyms GDB,  Golli MBP,  HMBPR,  HUGO,  Hemopoietic MBP,  MBP,  MBP_CAVPO,  MGC99675,  MLD,  Myelin A1 Protein,  Myelin A1 protein,  Myelin Deficient,  Myelin basic protein,  Myelin membrane encephalitogenic protein,  OTTHUMP00000,  OTTHUMP00000163776,  basic,  myelin basic protein
Swissprot
Cellular Localization Myelin membrane. Cytoplasmic side of myelin.
Concentration 100 μg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Neuroscience,  Tags and Cell Markers
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background MBP belongs to the myelin basic protein family. The classic group of MBP isoforms (isoform 4-isoform 14) are the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. MBP has six isoforms. Catalog#10458-1-AP is capable of recognizing multiple isoforms of MBP.
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Unconjugated

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