MANF Polyclonal Antibody (E-AB-12987)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human colon cancer |
| Dilution | IHC 1:100-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human MANF |
| Abbre | MANF |
| Synonyms | ARMET, ARMET protein, ARP, Arginine rich mutated in early stage tumors, Arginine rich protein, Arginine-rich protein, MANF, MGC142148, MGC142150, Manf, Mesencephalic astrocyte derived neurotrophic factor, Mesencephalic astrocyte-derived neurotrophic factor, Protein A |
| Swissprot | |
| Cellular Localization | Secreted. |
| Concentration | 0.1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related. |
Other Clones
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Other Formats
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Unconjugated
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