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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer, Human tonsil
Dilution IHC 1:30-1:150
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human LTB
Abbre LTB
Synonyms LT beta,  LT-beta,  Ltb,  Lymphotoxin-beta,  TNF-C,  TNFC,  TNFSF3,  Tumor necrosis factor C,  Tumor necrosis factor ligand superfamily member 3,  lymphotoxin beta,  p33
Swissprot
Cellular Localization Membrane.
Concentration 0.9 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Immunology,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Other Clones

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Unconjugated

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