LTB Polyclonal Antibody (E-AB-13743)

For research use only.
Verified Samples |
Verified Samples in IHC: Human liver cancer, Human tonsil |
Dilution | IHC 1:30-1:150 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human LTB |
Abbre | LTB |
Synonyms | LT beta, LT-beta, Ltb, Lymphotoxin-beta, TNF-C, TNFC, TNFSF3, Tumor necrosis factor C, Tumor necrosis factor ligand superfamily member 3, lymphotoxin beta, p33 |
Swissprot | |
Cellular Localization | Membrane. |
Concentration | 0.9 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Immunology, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Other Clones
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Other Formats
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Unconjugated
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