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For research use only.

Verified Samples Verified Samples in IHC: Human esophagus cancer
Dilution IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human LRIG3
Abbre LRIG3
Synonyms LIG-3,  LIG3,  LRIG1-3,  LRIG3,  Leucine-rich repeats and immunoglobulin-like domains protein 3,  Leucine-rich repeats- and immunoglobulin-like domains- containing protein 3,  Lrig3
Swissprot
Cellular Localization Cell membrane. Cytoplasmic vesicle membrane. Detected in cytoplasmic vesicles when coexpressed with ERBB4.
Concentration 1.2 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Developmental Biology,  Neuroscience,  Stem Cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Leucine-rich repeats and immunoglobulin-like domains 3 (Lrig3) was identified by microarray analysis among genes that show differential expression during gastrulation in Xenopus laevis.Lrig3 was expressed in the neural plate and neural crest (NC) at neurula stages, and in NC derivatives and other dorsal structures during tailbud stages.A prominent consequence of the morpholino-induced inhibition of Lrig3 expression was impaired NC formation, as revealed by the suppression of marker genes, including Slug, Sox9 and Foxd3.
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Unconjugated

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