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For research use only.

Verified Samples Verified Samples in IHC: Human ovarian cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human LDOC1
Abbre LDOC1
Synonyms BCUR1,  Breast cancer up regulated 1,  Breast cancer upregulated 1,  Gm366,  LDOC1,  Ldoc1,  Leucine zipper down regulated in cancer 1,  Leucine zipper protein d,  Leucine zipper protein down regulated in cancer cells
Swissprot
Cellular Localization Nucleus.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.
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Unconjugated

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