KLF1 Polyclonal Antibody (E-AB-19799)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human esophagus cancer, Human brain |
| Dilution | IHC 1:50-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human KLF1 |
| Abbre | KLF1 |
| Synonyms | CDAN4, EKLF, EKLF PEN, Erythroid Kruppel like factor, Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor), Erythroid krueppel-like transcription factor, Erythroid specific transcription factor EKLF, HBFQTL6, Human erythroid-specif |
| Swissprot | |
| Cellular Localization | Nucleus. Colocalizes with SUMO1 in nuclear speckles. |
| Concentration | 0.96 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4. |
Other Clones
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Other Formats
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Unconjugated
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