JPT1 Polyclonal Antibody (E-AB-52818)

Citations ({{ citationsPage.numTotal }}) Manual MSDS

All	Size	Price	Qty
	200μL	$ 399.00
	120μL	$ 240.00
	60μL	$ 143.00
	20μL	$ 73.00

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Verified Samples	Verified Samples in IHC: Human thyroid cancer, Human cervical cancer
Dilution	IHC 1:30-1:150
Isotype	IgG
Host	Rabbit
Reactivity	Human, Mouse, Rat
Applications	IHC
Clonality	Polyclonal
Immunogen	Fusion protein of human JPT1
Abbre	JPT1
Synonyms	ARM2, Androgen regulated protein 2, Androgen-regulated protein 2, HN1, HN1A, Hematological and neurological expressed 1, Hematological and neurological expressed 1 protein
Swissprot	Q9UK76
Cellular Localization	Nucleus.
Concentration	0.66 mg/mL
Buffer	Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method	Antigen affinity purification
Research Areas	Cell Biology
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background	Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).

Cat.No.	Product Name	Sizes
E-AB-1003	Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1194	HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed	500μL , 120μL , 1mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	50mL , 18mL , 6mL , 3mL
E-IR-R220	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50Assays

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Unconjugated