ITGB3BP Polyclonal Antibody (E-AB-10402)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human gastric cancer, Human brain |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ITGB3BP |
| Abbre | ITGB3BP |
| Synonyms | Beta 3 endonexin, Beta-3, Beta3 endonexin, Beta3 endonexin long form, CENP R, CENPR, Centromere protein R, HSU37139, Integrin beta 3 binding protein, Integrin beta 3 binding protein (beta3-endonexin), NRIF 3, NRIF3, Nuclear receptor interacting factor, endonexin |
| Swissprot | |
| Cellular Localization | Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Cytoplasm. Isoform 4: Cytoplasm. Note=Localizes in the centromeres. Isoform 3 is predominantly nuclear and weakly cytoplasmic. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. |
Other Clones
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Other Formats
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Unconjugated
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