IREB2 Polyclonal Antibody (E-AB-62801)

Citations ({{ citationsPage.numTotal }}) Manual MSDS

All	Size	Price	Qty
	200μL	$ 530.00
	120μL	$ 320.00
	60μL	$ 200.00

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Verified Samples	Verified Samples in IF: A549
Dilution	IF 1:20-1:50
Isotype	IgG
Host	Rabbit
Reactivity	Human, Mouse, Rat
Applications	IF
Clonality	Polyclonal
Immunogen	Recombinant fusion protein of human IREB2 (NP_004127.1).
Abbre	IREB2
Synonyms	ACO3, IREB2, IRP2, IRP2AD
Swissprot	P48200
Cellular Localization	Cytoplasm.
Concentration	1 mg/mL
Buffer	Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method	Affinity purification
Research Areas	Cardiovascular, Metabolism
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background	The protein encoded by this gene is an RNA-binding protein that acts to regulate iron levels in the cells by regulating the translation and stability of mRNAs that affect iron homeostasis under conditions when iron is depleted. When iron levels are low, this protein binds to iron-responsive elements (IRES), stem-loop structures located either in the 5' or 3' UTRs. Binding to the 5' UTR represses translation, while binding to the 3' UTR inhibits mRNA degradation. When iron is found in the cell, this protein is degraded in a F-box and leucine rich repeat protein 5-dependent manner. Variants in this gene have been associated with lung cancer and chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants encoding different isoforms.

Cat.No.	Product Name	Sizes
E-AB-1003	Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1010	Goat Anti-Rabbit IgG(H+L)(Cyanine3 conjugated)	500μL , 120μL , 60μL
E-AB-1014	Goat Anti-Rabbit IgG(H+L)(FITC conjugated)	500μL , 120μL , 60μL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1060	Goat Anti-Rabbit IgG(H+L)(Elab Fluor^® 594 conjugated)	500μL , 120μL , 60μL
E-AB-1075	Goat Anti-Rabbit IgG(H+L)(Elab Fluor^® 647 conjugated)	500μL , 120μL , 60μL
E-AB-1099	Elab Fluor^® Violet 450-Goat Anti-Rabbit IgG(H+L)	500μL , 120μL , 1mL
E-AB-1194	HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed	500μL , 120μL , 1mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	50mL , 18mL , 6mL , 3mL
E-IR-R220	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50Assays

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Unconjugated