Insulin Receptor/INSR/CD220 Monoclonal Antibody (AN200037P)

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	100μL	$ 320.00

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Verified Samples	Verified Samples in IHC: Human placenta, Human kidney
Dilution	IHC-P 1:100-1:500,
Isotype	IgG1
Host	Mouse
Reactivity	Human
Applications	IHC-P
Clonality	Monoclonal
Immunogen	Recombinant Human Insulin Receptor/INSR/CD220 Protein
Abbre	INSR
Synonyms	HHF, CD220, HHF5, INSR, IR, Insulin R, INSR, IR, Insulin Receptor
Swissprot	P06213
Concentration	1 mg/mL
Buffer	0.2 μm filtered solution in PBS
Purification Method	Protein A
Research Areas	Signal Transduction, Neuroscience, Cancer, Cardiovascular, Metabolism, Developmental Biology
Clone No.	12G3
Conjugation	Unconjugated
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping	Ice bag
background	This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

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Unconjugated