Insulin Polyclonal Antibody (E-AB-70202)

For research use only.
Verified Samples |
Verified Samples in IHC: Mouse pancreas |
Dilution | IHC 1:200-1:1000 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein corresponding to Mouse insulin |
Abbre | Insulin |
Synonyms | IDDM, IDDM1, IDDM2, ILPR, INS, IRDN, Insulin A chain, Insulin B chain, MODY10, Preproinsulin, Proinsulin, Proinsulin precursor, ins |
Swissprot | |
Cellular Localization | Secreted |
Concentration | 300 μg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Insulin is a peptide hormone,produced by beta cells of the pancreas,and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization,protein synthesis and in the formation and storage of neutral lipids. Insulin is synthesized as a precursor molecule,proinsulin,which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin,while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in insulin results in type 1 diabetes mellitus. Insulin may also exist 36 kDa form corresponding to the hexameric insulin form. |
Other Clones
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Other Formats
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Unconjugated
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