INSC Polyclonal Antibody (E-AB-18117)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human tonsil, Human liver cancer |
| Dilution | IHC 1:50-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human INSC |
| Abbre | INSC |
| Synonyms | INSC, Insc, Inscuteable homolog (Drosophila), Protein inscuteable homolog |
| Swissprot | |
| Cellular Localization | Cytoplasm. Localizes to the apical cortex of mitotic epidermal cells and to the apical side of neuronal progenitor cells. |
| Concentration | 1.92 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cell Biology, Developmental biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]). |
Other Clones
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Other Formats
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Unconjugated
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