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For research use only.

Verified Samples Verified Samples in WB: 231, 293T, Raji, Hela
Verified Samples in IHC: Human thyroid cancer, Human cervical cancer
Dilution WB 1:500-1:2000,  IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human IL2RB
Abbre IL2RB
Synonyms P70,  IL2RB,  CD122,  IL15RB,  P70-75,  IL-2Rβ,  p75,  IL-2RB,  Interleukin-2 receptor subunit beta,  IL-2 receptor subunit beta,  IL-2R subunit beta,  High affinity IL-2 receptor subunit beta,  Interleukin-15 receptor subunit beta,  p70-75 (p75),  IL-2R&,  beta,  CD122 antigen,  High affinity IL 2 receptor beta subunit,  High affinity IL 2 receptor subunit beta,  IL2 receptor,  Interleukin 2 receptor beta,  interleukin 2 receptor subunit beta,  P70 75,  P7075
Swissprot
Calculated MW 61 kDa
Cellular Localization Membrane.
Concentration 0.3 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Immunology,  Signal Transduction,  Stem Cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
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Unconjugated

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