IL12B Monoclonal Antibody (AN200248P)
For research use only.
| Verified Samples | Verified Samples in IHC: Mouse spleen |
| Dilution | IHC-P 1:100-1:500 |
| Isotype | IgG1 |
| Host | Mouse |
| Reactivity | Mouse |
| Applications | IHC-P |
| Clonality | Monoclonal |
| Immunogen | Recombinant Mouse IL12B Protein |
| Abbre | IL12B |
| Synonyms | NKSF, IL-12/IL-23 p, IL-12 subunit p, NK cell stimulatory factor chain, NK cell Stimulating Factor Chain, CLMF, CLMF p, IL12 p, CLMF2, Cytotoxic lymphocyte maturation factor 40 kDa subunit, Cytotoxic Lymphocyte Maturation Factor 40 kDa subunit (CLMF p40), IL12, IL-12 p40, IL12 p70, IL-12 p70, IL-12/IL-23 p40, NK cell Stimulating Factor Chain 2, p40, IL-12B, NKSF2, Interleukin-12 subunit beta, CLMF p40, IL-12 subunit p40, NK cell stimulatory factor chain 2, IL 12B, Il12b |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Clone No. | 10A7 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.1 PublicationAssociates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
Other Clones
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Other Formats
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Unconjugated
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