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For research use only.

Verified Samples Verified Samples in IF: MCF-7
Dilution IF 1:50-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human IKZF3 (NP_036613.2).
Abbre IKZF3
Synonyms AIO,  AIOLOS,  IKZF3,  ZNFN1A3
Swissprot
Cellular Localization Nucleus. Cytoplasm.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.
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Unconjugated

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