IFITM2 Polyclonal Antibody (E-AB-18890)

For research use only.
Verified Samples |
Verified Samples in IHC: Human tonsil, Human brain |
Dilution | IHC 1:30-1:150 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Fusion protein of human IFITM2 |
Abbre | IFITM2 |
Synonyms | 1 8D, DSPA2c, Dispanin subfamily A member 2c, IFITM 2, Interferon induced transmembrane protein 2, Interferon induced transmembrane protein 2 (1 8D), Interferon inducible protein 1 8D |
Swissprot | |
Cellular Localization | Membrane, Multipass membrane protein. |
Concentration | 0.72 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Cancer, Immunology |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | IFITM2,also named as 1-8D,belongs to the CD225 family. It is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens,namely influenza A H1N1 virus,West Nile virus (WNV),and dengue virus (WNV),by inhibiting the early step(s) of replication. IFITM2 induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. It is overexpressed in colon carcinoma. IFITM2 is a novel pro-apoptotic gene that will provide new insights into the regulated cellular pathways to death. This antibody is specific to IFTIM2. |
Other Clones
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Other Formats
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Unconjugated
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