IDS Polyclonal Antibody (E-AB-53138)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human brain, Human prostate cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human IDS |
| Abbre | IDS |
| Synonyms | AW214631, Alpha L iduronate sulfate sulfatase, Alpha-L-iduronate sulfate sulfatase, IDS, Ids, Iduronate 2 sulfatase, Iduronate 2 sulfatase 14 kDa chain, Iduronate 2 sulfatase 42 kDa chain, Iduronate 2-sulfatase 14 kDa chain, Iduronate sulfatase, Idursulfase, MPS2, RP |
| Swissprot | |
| Cellular Localization | Lysosome. |
| Concentration | 1.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome,an X chromosome-linked disease. An internal proteolytic cleavage occurs to produce the mature IDS present in human liver shown to contain a 42 kDa polypeptide N-terminal to a 14 kDa polypeptide. |
Other Clones
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Other Formats
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Unconjugated
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