ICA1 Polyclonal Antibody (E-AB-53153)

For research use only.
Verified Samples |
Verified Samples in IHC: Human esophagus cancer, Human brain |
Dilution | IHC 1:50-1:100 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Fusion protein of human ICA1 |
Abbre | ICA1 |
Synonyms | 69 kDa islet cell autoantigen, Diabetes mellitus type I autoantigen, ICA 1, ICA69, ICAp69, Ica1, Islet cell autoantigen 1, Islet cell autoantigen 1 (69kD), Islet cell autoantigen 1 69kDa, Islet cell autoantigen 1 isoform, Islet cell autoantigen p69, OTTHUMP000 |
Swissprot | |
Cellular Localization | Cytoplasm>cytosol. Golgi apparatus membrane. Cytoplasmic vesicle>secretory vesicle membrane. Cytoplasmic vesicle>secretory vesicle>synaptic vesicle membrane. Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules. |
Concentration | 0.84 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Immunology, Neuroscience |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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