Human VEGFR-2/KDR Antibody Pair Set (E-KAB-0472)
For research use only.
| Background |
Vascular endothelial growth factor ( VEGF ) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor , known as kinase insert domain receptor , is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation , survival , migration , tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors , including Rab GTPase , P2Y purine nucleotide receptor , integrin alphaVbeta3 , T-cell protein tyrosine phosphatase , etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
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| Synonyms |
VEGFR2, CD309, FLK1
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human VEGFR-2/KDR in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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