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| Background | This gene encodes a member of the peptidase M10 family of matrix metalloproteinases ( MMPs ) . Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes , such as embryonic development , reproduction , and tissue remodeling , as well as in disease processes , such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin , laminin , elastin , proteoglycan core protein , gelatins , and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11. |
| Synonyms | MMP10, SL-2, STMY2, Stromelysin-2, Transin-2 |
| Swissprot | |
| Reactivity | Human |
| Specificity | Detects Human MMP-10 in ELISAs |
| Applications | ELISA |
| Storage | -20℃ |
| Expiration date | 12 months |
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