Human IL-8 Antibody Pair Set (E-KAB-0047)
For research use only.
| Background |
Interleukin 8 (IL-8),also known as CXCL8,which is a member of the CXC chemokine family. This chemokine is secreted by a variety of cell types including monocyte/macrophages,T cells,neutrophils,fibroblasts,endothelial cells,and various tumor cell lines in response to inflammatory stimuli. IL-8 has two primary functions. It induces chemotaxis in target cells,primarily neutrophils but also other granulocytes,causing them to migrate toward the site of infection. IL-8 also induces phagocytosis once they have arrived. This gene is believed to play a role in the pathogenesis of bronchiolitis,a common respiratory tract disease caused by viral infection. IL-8 is also known to be a potent promoter of angiogenesis. IL-8 has been associated with tumor angiogenesis,metastasis,and poor prognosis in breast cancer. IL-8 may present a novel therapeutic target for estrogen driven breast carcinogenesis and tumor progression.
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| Synonyms |
CXCL8, GCP-1, GCP1, IL8, MDNCF, MONAP, NAF, NAP-1, NAP1, Interleukin-8, IL-8, Emoctakin, C-X-C motif chemokine 8, Chemokine (C-X-C motif) ligand 8, Granulocyte chemotactic protein 1 (GCP-1), Monocyte-derived neutrophil chemotactic factor (MDNCF)
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human IL-8 in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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| Introduction |
This Antibody Pair Kit applies to the sandwich ELISA assay.
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