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For research use only.
| Background | This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation , maturation , recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor , which is a heterodimer , whose beta subunit is shared with the receptors for interleukine 3 ( IL3 ) and colony stimulating factor 2 ( CSF2/GM-CSF ) . This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 ( IL4 ) , interleukin 13 ( IL13 ) , and CSF2 . This gene , IL4 , and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. |
| Synonyms | IL5, EDF, TRF, E-CSF, ESGF |
| Swissprot | |
| Reactivity | Human |
| Specificity | Detects Human IL-5 in ELISAs |
| Applications | ELISA |
| Storage | -20℃ |
| Expiration date | 12 months |
Other Clones
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Other Formats
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