Human IL-1R2 Antibody Pair Set (E-KAB-0409)
For research use only.
| Background |
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha ( IL1A ) , interleukin beta ( IL1B ) , and interleukin 1 receptor , type I ( IL1R1/IL1RA ) , and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 ( IL4 ) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.
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| Synonyms |
IL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human IL-1R2 in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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Other Clones
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