Human IgG3 Antibody Pair Set (E-KAB-0446)
For research use only.
| Background |
Constant region of immunoglobulin heavy chains. Immunoglobulins , also known as antibodies , are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity , the membrane-bound immunoglobulins serve as receptors which , upon binding of a specific antigen , trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity , which results in the elimination of bound antigens.The antigen binding site is formed by the variable domain of one heavy chain , together with that of its associated light chain. Thus , each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V- ( D ) -J rearrangement and can then be subjected to somatic hypermutations which , after exposure to antigen and selection , allow affinity maturation for a particular antigen
|
| Synonyms |
IGHG3
|
| Swissprot | |
| Reactivity |
Human
|
| Specificity |
Detects Human IgG3 in ELISAs
|
| Applications |
ELISA
|
| Storage |
-20℃
|
| Expiration date |
12 months
|
Other Clones
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