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For research use only.
| Background | This gene encodes a member of the S1 , or chymotrypsin , family of serine peptidases. This protease catalyzes the cleavage of factor B , the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine , a cell signaling protein secreted by adipocytes , which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency , which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. |
| Synonyms | ADN, Adipsin, DF, PFD, Factor D, Properdin Factor D Esterase |
| Swissprot | |
| Reactivity | Human |
| Specificity | Detects Human CFD in ELISAs |
| Applications | ELISA |
| Storage | -20℃ |
| Expiration date | 12 months |
Other Clones
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Other Formats
1 Results
