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50μL&100μg $ 499.00
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For research use only.

Background
This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants.
Synonyms
C5
Swissprot
Reactivity
Human
Specificity
Detects Human C5a in ELISAs
Applications
ELISA
Storage
-20℃
Expiration date
12 months
Introduction
This Antibody Pair Kit applies to the sandwich ELISA assay.
Other Clones

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