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For research use only.

Verified Samples Verified Samples in IF: L929, U2OS
Dilution IF 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human HSPA2 (NP_068814.2).
Abbre HSPA2
Synonyms HSP70-2,  HSP70-3,  HSPA2
Swissprot
Cellular Localization Cytoskeleton, meiotic spindle, Cytosol, Extracellular region or secreted, blood microparticle, extracellular exosome, Mitochondrion, Nucleus, male germ cell Nucleus, synaptonemal complex, Plasma Membrane, CatSper complex, Other locations: cell surface, membrane, myelin sheath.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Human HSPA2 is a member of the HSPA (HSP70) family of heat-shock proteins,encoded by the gene originally described as testis-specific. Recently,it has been reported that HSPA2 can be also expressed in human somatic tissues in a cell-type specific manner. HSPA2 is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. HSPA2 is involved in sperm maturity,function and fertility. Aberrant expression of HSPA2 in testes has been connected with male infertility. Recently,HSPA2 has attracted increased interest due to its possible involvement in carcinogenesis of non-testicular tissues. This antibody well recognized the endogenous HSPA4 protein in testis and multiple cell lines. (21373891)
Other Clones

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Unconjugated

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