HSP105 Polyclonal Antibody (E-AB-10380)

For research use only.
Verified Samples |
Verified Samples in WB: PC-3, Human colon cancer, Human liver cancer |
Dilution | WB 1:500-1:2000 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | WB |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human HSPH1 |
Abbre | HSPH1 |
Synonyms | Antigen NY CO 25, Antigen NY-CO-25, DKFZp686M05240, He, Heat shock 105kD, Heat shock 105kD alpha, Heat shock 105kD beta, Heat shock 105kDa protein, Heat shock 105kDa protein 1, Heat shock 105kDa/110kDa protein 1, Heat shock 110 kDa protein, Heat shock 110kDa protein |
Swissprot | |
Calculated MW | 97 kDa |
Cellular Localization | Cytoplasm. |
Concentration | 0.2 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Heat shock protein 105 kDa is a protein that in humans is encoded by the HSPH1 gene.Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly.Inhibits HSPA8/HSC70 ATPase and chaperone activities.Highly expressed in testis.Present at lower levels in most brain regions, except cerebellum.Overexpressed in cancer cells.Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity. |
Other Clones
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Other Formats
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Unconjugated
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