HSD17B2 Polyclonal Antibody (E-AB-11304)
For research use only.
| Verified Samples |
Verified Samples in WB: Human liver Verified Samples in IHC: Human esophagus cancer, Human brain |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human HSD17B2 |
| Abbre | HSD17B2 |
| Synonyms | 17 beta HSD 2, 17-beta-HSD 2, 17-beta-hydroxysteroid dehydrogenase type 2, 20 alpha HSD, 20 alpha hydroxysteroid dehydrogenase, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, DHB2, E2DH, EDH17B2, Estradiol 17-beta-dehydrogenase 2, HSD17, Hsd17b2, Hydroxysteroid |
| Swissprot | |
| Calculated MW | 43 kDa |
| Cellular Localization | Membrane. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | 17β-HSD2 (17β hydroxysteroid dehydrogenase type 2) belongs to the 17β-HSD family of proteins that regulate the availability of steroids within a tissue. 17β-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17β-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis. |
Other Clones
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Other Formats
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Unconjugated
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