HSD17B1 Polyclonal Antibody (E-AB-65790)

Citations ({{ citationsPage.numTotal }}) Manual MSDS

All	Size	Price	Qty
	200μL	$ 530.00
	120μL	$ 320.00
	60μL	$ 200.00

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Verified Samples	Verified Samples in IHC: Human placenta, Mouse heart Verified Samples in IF: C6, HeLa
Dilution	IHC 1:50-1:200, IF 1:50-1:200
Isotype	IgG
Host	Rabbit
Reactivity	Human, Mouse, Rat
Applications	IHC, IF
Clonality	Polyclonal
Immunogen	Recombinant fusion protein of human HSD17B1 (NP_000404.2).
Abbre	HSD17B1
Synonyms	17-beta-HSD, 20-alpha-HSD, E2DH, EDH17B2, EDHB17, HSD17, HSD17B1, SDR28C1
Swissprot	P14061
Cellular Localization	Cytoplasm.
Concentration	1 mg/mL
Buffer	Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method	Affinity purification
Research Areas	Cancer, Metabolism, Neuroscience, Signal Transduction
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background	Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP(H) over NAD(H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy.

Cat.No.	Product Name	Sizes
E-AB-1003	Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1010	Goat Anti-Rabbit IgG(H+L)(Cyanine3 conjugated)	500μL , 120μL , 60μL
E-AB-1014	Goat Anti-Rabbit IgG(H+L)(FITC conjugated)	500μL , 120μL , 60μL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1060	Goat Anti-Rabbit IgG(H+L)(Elab Fluor^® 594 conjugated)	500μL , 120μL , 60μL
E-AB-1075	Goat Anti-Rabbit IgG(H+L)(Elab Fluor^® 647 conjugated)	500μL , 120μL , 60μL
E-AB-1099	Elab Fluor^® Violet 450-Goat Anti-Rabbit IgG(H+L)	500μL , 120μL , 1mL
E-AB-1194	HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed	500μL , 120μL , 1mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	50mL , 18mL , 6mL , 3mL
E-IR-R220	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50Assays

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Unconjugated