HMGA1 Polyclonal Antibody (E-AB-17331)

For research use only.
Verified Samples |
Verified Samples in IHC: Human colon cancer, Human cervical cancer |
Dilution | IHC 1:50-200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human HMGA1 |
Abbre | HMGA1 |
Synonyms | High mobility gr, High mobility group (nonhistone chromosomal) protein isoforms I and Y, High mobility group AT hook 1, High mobility group AT-hook protein 1, High mobility group protein 1, High mobility group protein A1, High mobility group protein HMG-I/HMG-Y |
Swissprot | |
Cellular Localization | Nucleus. Chromosome. |
Concentration | 0.6 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling, Microbiology |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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