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For research use only.

Verified Samples Verified Samples in IF: U-2OS, HeLa
Dilution IF 1:50-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IF
Clonality Polyclonal
Immunogen A synthetic peptide of human Histone H2AX.
Abbre Histone H2AX
Synonyms H2A.X,  H2A/X,  H2AFX,  H2AX,  Histone H2AX,  gamma H2A.X,  histone H2AX,  γH2AX
Swissprot
Cellular Localization Nucleus. Chromosome.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
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Unconjugated

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