HIRIP3 Polyclonal Antibody (E-AB-61469)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Rat liver, Rat spleen, Human liver cancer, Human oophoroma, Human skin carcinoma, Human kidney Verified Samples in IF: U2OS |
| Dilution | IHC 1:50-1:200, IF 1:50-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human HIRIP3 (NP_003600.2). |
| Abbre | HIRIP3 |
| Synonyms | HIRIP3 |
| Swissprot | |
| Cellular Localization | Nucleus. Nuclear throughout the cell cycle and is excluded from condensed chromatin during mitosis. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling, Developmental biology, Stem cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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