HDAC6 Polyclonal Antibody (E-AB-14126)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human breast cancer, Human cervical cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human HDAC6 |
| Abbre | HDAC6 |
| Synonyms | CPBHM, FLJ16239, HD 6, HD6, HDAC 6, HDAC6, Histone deacetylase 6, Histone deacetylase 6 (HD6), JM 21, JM21, KIAA0901, OTTHUMP00000032398, OTTHUMP00000197663, PPP1R90, Protein phosphatase 1 regulatory subunit 90 |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm. It is mainly cytoplasmic, where it is associated with microtubules. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. |
Other Clones
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Other Formats
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Unconjugated
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