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For research use only.

Verified Samples Verified Samples in IHC: Human lung cancer, Human breast cancer, Mouse testis, Rat brain
Dilution IHC 1:200-1:1000
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein corresponding to Mouse HDAC1
Abbre HDAC1
Synonyms DKFZp686H12203,  GON 10,  HD1,  HDAC 1,  HDAC1,  Histone deacetylase 1,  RPD3,  RPD3L1,  Reduced potassium dependency yeast homolog like 1
Swissprot
Cellular Localization Nucleus.
Concentration 310 μg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Epigenetics and Nuclear Signaling,  Stem Cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
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Unconjugated

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