GRIN2A Polyclonal Antibody (E-AB-17358)

For research use only.
Verified Samples |
Verified Samples in IHC: Human esophagus cancer, Human cerebellum |
Dilution | IHC 1:25-100 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human GRIN2A |
Abbre | GRIN2A |
Synonyms | EPND, FESD, GRIN 2A, GRIN2A, GluN2A, Glutamate [NMDA] receptor subunit epsilon-1, Glutamate receptor, Glutamate receptor ionotropic N methyl D aspartate 2A, LKS, N Methyl D Aspartate Receptor Subtype 2A, N methyl D aspartate receptor channel, hNR2A, subunit epsilon 1 |
Swissprot | |
Cellular Localization | Cell membrane. Cell junction>synapse>postsynaptic cell membrane. |
Concentration | 0.5 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Neuroscience |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants. |
Other Clones
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Other Formats
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Unconjugated
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