Granzyme B Monoclonal Antibody (ELAB5024-R)
For research use only.
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC-P |
| Synonyms | Granzyme B |
| Cellular Localization | Cytoplasm |
| Tissue Specificity | Tonsil |
| Storage | The concentrated should be stored at -20°C protecting from light,Valid for 12 months. |
| Shipping | Ice bag |
| background | Granzyme B is a serine protease, which mediates the apoptosis signaling pathway of cytotoxic T lymphocytes (CTL) and natural killer cells (NK). Granzyme B is synthesized in the form of inactive protease, stored in lysosomal granules and released during the degradation of effector cells. The results shows that granzyme B is expressed in peripheral T-cell lymphoma (PTCL) and NK cell lymphoma by immunohistochemistry. The expression of cytotoxic proteins may play an important role in the differentiation and classification of peripheral T-cell and NK cell lymphoma, such as granzyme B, because many tumors of this type do not have specific morphology and phenotype. |
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