GPER1 Polyclonal Antibody (E-AB-65746)

For research use only.
Verified Samples |
Verified Samples in IF: C6, NIH/3T3, U2OS |
Dilution | IF 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IF |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein of human GPER1 (NP_001496.1). |
Abbre | GPER1 |
Synonyms | CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPER1, GPER1 , GPR30, LERGU, LERGU2, LyGPR, mER |
Swissprot | |
Cellular Localization | Cell membrane. Endoplasmic reticulum membrane. Golgi apparatus membrane. Protein has been detected in the cell membrane, endoplasmic reticulum and Golgi apparatus. It is currently unclear whether this is a cell surface or intracellular receptor. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling, Metabolism, Neuroscience, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. |
Other Clones
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Other Formats
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Unconjugated
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