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200μL $ 399.00
120μL $ 240.00
60μL $ 143.00
20μL $ 73.00
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For research use only.

Verified Samples Verified Samples in WB: Mouse brain
Verified Samples in IHC: Human liver cancer
Dilution WB 1:200-1:1000,  IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
ClonalityPolyclonal
ImmunogenRecombinant protein of human GNAS
AbbreGNAS
SynonymsAHO,  C20orf45,  GNAS1,  GPSA,  GSA,  GSP,  NESP,  PHP1A,  PHP1B,  PHP1C,  POH
Swissprot
Calculated MW46 kDa
Cellular LocalizationCytosol, Extracellular region or secreted, extracellular exosome, Golgi apparatus, trans-Golgi network membrane, Plasma Membrane, heterotrimeric G-protein complex, plasma membrane, Other locations: cytoplasm, intrinsic component of membrane, membrane.
Concentration0.4 mg/mL
BufferPhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification MethodAffinity purification
Research AreasCancer,  Metabolism,  Signal Transduction
ConjugationUnconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
ShippingThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
backgroundThis locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses.
Other Clones

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    Other Formats

    1 Results

    Unconjugated

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