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For research use only.

Verified Samples Verified Samples in IHC: Human tonsil, Human cervical cancer
Dilution IHC 1:50-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human GMDS
Abbre GMDS
Synonyms 6 dehydratase,  GDP D mannose dehydratase,  GDP mannose 4 6 dehydratase,  GDP-D-mannose dehydratase,  GDP-mannose 4,  GMD,  GMDS,  Gmds,  OTTHUMP00000017756,  OTTHUMP00000232770,  SDR3E1,  Short chain dehydrogenase/reductase family 3E member 1
Swissprot
Concentration 1.26 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cancer,  Metabolism,  Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).
Other Clones

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Unconjugated

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