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For research use only.
| Host | Mouse |
| Reactivity | Human |
| Applications | IHC-P |
| Synonyms | GATA3 |
| Cellular Localization | nucleus |
| Tissue Specificity | Breast cancer |
| Storage | The concentrated should be stored at -20°C protecting from light,Valid for 12 months. |
| Shipping | Ice bag |
| background | GATA binding protein 3 (GATA3) is a member of the GATA family of transcription factors (including six members: GATA-1 to GATA-6). It plays an important role in promoting and guiding cell proliferation, development and differentiation in many tissues and cell types. GATA-3 is widely expressed in the epithelial cells of mammary duct glandular cavity and urinary tract epithelium, but not in myoepithelial cells. The expression of GATA-3 is closely associated with the expression of estrogen receptor-α in breast cancer,and there is evidence that GATA-3 can be used to predict the response to hormone therapy in breast cancer patients, and has also been shown to be a new marker for bladder cancer. |
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