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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer, Human brain
Dilution IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
ClonalityPolyclonal
ImmunogenSynthetic peptide of human GAD2
AbbreGAD2
Synonyms65 kDa glutamic acid decarboxylase,  DCE 2,  DCE2,  GAD 2,  GAD 65,  GAD-2,  GAD-65,  Gad2,  Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa),  Glutamate Decarboxylase 65,  Glutamate decarboxyla,  Glutamate decarboxylase 2,  Glutamate decarboxylase 2 (pancreas)
Swissprot
Cellular LocalizationCytoplasm>cytosol. Cytoplasmic vesicle. Cell junction>synapse>presynaptic cell membrane. Golgi apparatus membrane. Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters.
Concentration0.3 mg/mL
BufferPhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification MethodAffinity purification
Research AreasCancer,  Metabolism,  Neuroscience
ConjugationUnconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
ShippingThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
backgroundThis gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Other Clones

1 Results

    Other Formats

    1 Results

    Unconjugated