FUT3 Polyclonal Antibody (E-AB-17979)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human cervical cancer, Human ovarian cancer |
| Dilution | IHC 1:40-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human FUT3 |
| Abbre | FUT3 |
| Synonyms | Lewis blood group), 3/1, 4)-fucosyltransferase, Alpha-(1, Blood group Lewis alpha-4-fucosyltransferase, CD174, FT3B, FUT3, FucT III, FucT-III, Fucosyltransferase 3, Fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Fucosyltransferase III, Galactoside |
| Swissprot | |
| Cellular Localization | Golgi apparatus>Golgi stack membrane. Membrane-bound form in trans cisternae of Golgi. |
| Concentration | 1.08 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cardiovascular |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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