FOXO4 Polyclonal Antibody (E-AB-53430)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human gastric cancer, Human breast cancer |
| Dilution | IHC 1:50-1:350 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human FOXO4 |
| Abbre | FOXO4 |
| Synonyms | 7, AFX, AFX1, ALL1-fused gene from X chromosome, Afxh, FOXO 4, FOXO4, Fork head domain transcription factor AFX1, Forkhead box O4, Forkhead box protein O4, Foxo4, MGC117660, MGC120490, MLLT7, Mixed lineage leukemia, Myeloid/lymphoid or mixed lineage leuk, translocated to |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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